Medications, marijuana and your CDL

Updated October 2026

List every medication you take at your exam. Some may need a note from your prescribing doctor saying they're safe for driving.

Marijuana

DOT drug-testing rules still prohibit marijuana use by CDL drivers in safety-sensitive jobs, even in states where it's legal, and even with a medical marijuana card.

Over-the-counter medicines

Some cold and allergy medicines cause drowsiness. Read the labels and don't drive impaired.

General information, not medical advice.

General information, not medical advice. Your certified medical examiner decides whether you qualify and for how long.

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